I have been researching this one for a while now and will be bringing out a series of articles on the topic because it is really quite an in depth one!

One of the key reasons we want to use Progesterone cream is to really just give ourselves a chance to heal from existing Endometriosis. It can often feel like an uphill battle trying to beat this thing! We are constantly forming new cells in the wrong places and with excess Estrogens being a common symptom of Endometriosis, these cells are simply encouraged to grow more.


Let me explain this one a little more. Essentially, Oestrogens and Progesterones oppose each other in our bodies. They need to work on a jing jang effect – neither should be higher than the other and each one should level each other out. If we are lacking in Progesterone, our oestrogen will go up. If we are lacking in oestrogen, our progesterone will go up.  We don’t want either to be too high or too low. They need to both exist in perfect balance with eachother. Many women with Endometriosis suffer from Oestrogen Dominance – in other words they don’t have enough progesterone to balance out the estrogen and therefore have too much estrogen. Estrogen creates growth. That is it’s main function. It will draw with it a series of symptoms which are all in line with wanting to create growth, many of which we are familiar with.


Here is a comprehensive list of symptoms you may experience with estrogen dominance:

  • Acceleration of aging
  • Increased body fat and weight gain
  • Salt and fluid retention
  • Breast tenderness
  • Foggy thinking
  • Depression, anxiety and headaches
  • Cyclical migraines
  • Impairs blood sugar levels
  • Impairs the thyroid function – particularly hypothyroidism
  • Little or low libido
  • Increase risk of blood clots and growth
  • Cell proliferation in “womanly bits” – breast growths, fibroids, endometrial cells, cancers
  • Dilates blood vessels
  • Triggers autoimmune diseases and responses – like allergies and skin sensitivities
  • Bladder infections and bladder issues – possibly even Interstitial Cystitis
  • Loss of zinc and retention of copper
  • Increase risk of gallbladder disease
  • Miscarriages
  • PMS



It is likely that you don’t have all of these symptoms or even to the extent of them. We are all different and it is important to test your hormone levels before using any specific progesterone cream for levelling out your hormones – mainly so you know where you are at and can measure if they are working for you. There are a number of other imbalances in the body which can actually illustrate very similar symptoms and you may be “barking up the wrong tree”. Hypothyroidism often displays many similar symptoms to estrogen dominance and the approach would be quite different in treating that one.

However, there is also no inherent danger in using progesterone cream – according to Dr John Lee. He expresses that the only way progesterone creams can be harmful is if they are not real progesterone and if too high a dosage is used. You can read his book to gain a full comprehensive understanding of progesterone cream.I have been researching this one for a while now and will be brining out a series of articles on the topic because it is really quite an in depth one!

Real progesterone will actually be listed as an ingredient in the cream – it is not wild yam or progestin. Progestin is a pharmaceutically created product and your body will not be able to synthesise this correctly or expel it correctly. It needs to actually list progesterone as an ingredient.

How to use Progesterone Cream

Progesterone will stay in your body for up to 12hrs. The levels will be at their highest at 3/4hrs after use. It is best to take progesterone in the morning and at night.
• Use no more than 20mg per day – just measure your body and see how it feels. If you start to get any adverse symptoms, simply lower the dose. It is okay to experiment and work out what your body needs – according to Dr John Lee.
• Rotate where you apply it – don’t put it on the same place every day.
• Put it on the thin areas of skin – the face, neck, chest, inside arm
• Spread it wide! Spread over a larger area of skin to get the best absorption
• Apply after showering or bathing

My personal opinion on Progesterone Cream and how they fit in with healing endo

I think progesterone creams can certainly help us feel better. They will lower the proliferation of cells forming and growing in the wrong places! What they can do is give us a chance to rectify the problem – the cells are at their smallest and we can then flush them out and reduce the inflammatory response in the area by flushing out more toxins.
I personally don’t believe it is a long term fix for endo. – Just my opinion. I think endo is not just about regulating hormones and cell growth. The endo got there due to a different imbalance and progesterone cream doesn’t get to the source of that imbalance.

I would personally only recommend taking progesterone cream for about 4months and see if it has helped. Use that time to focus on healing the rest of your body – like your liver and your colon etc.

I am going to be doing heaps more research on the subject so you never know I might feel differently about it in a few months but for now…. These are my thoughts. If you have used progesterone cream please feel free to share. – positive or negative. It is worth sharing so others can learn more.

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